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EPIEN Medical Releases ORALMEDIC(R) Barrier Solution Over The Counter in Canada.

MINNETONKA, Minn. -- EPIEN Medical, Inc., ("EPIEN") announced today that it has commenced OTC distribution of its new oral ulcer treatment product, ORALMEDIC[R] Barrier Solution, in Canada. Product distribution will be handled by a partnership between Axel Kraft and Corum Marketing of Toronto. Initially,

ORALMEDIC[R] will be available in selected Rexall Pharma Plus pharmacies and A&P and Dominion stores during the second week of November 2006.

ORALMEDIC[R] Barrier Solution is the only OTC product available in the world that immediately and permanently ends oral ulcer pain with one ten-second treatment. Canada joins the U.K. as the first countries offering the product to their consumers. Approval to release the product in the United States is currently pending FDA regulatory review.

Commenting on the need for such a product in the market place Steve Corrick, President of Corum Marketing, noted "There are no other products like this one and we are pleased to be part of its early distribution with EPIEN".

EPIEN's CEO Reginald Dupre stated that "We are excited to follow our spring U.K. release of ORALMEDIC[R] Barrier Solution with this fall's release in Canada. We look forward to success with the Axel Kraft/Corum Marketing relationship".

EPIEN Medical is a privately held medical device company focused on developing, manufacturing, and marketing novel agents for the repair of damaged skin. The Company's initial approved products treat oral ulcers by quickly and permanently relieving pain by cleansing and sealing the lesion with a single, easy-to-use, ten-second treatment.

Additional corporate information is available at www.epien.com.

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