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Liver toxicity warning.

Patients taking either boosted or unboosted Invirase (saquinavir, hard gel capsules) or Fortavase (saquinavir, soft-gel capsules) should not take rifampin (brand names include Rifadin and Rimactane), a med used to treat bacterial infections like tuberculosis. A study conducted in HIV-negative

volunteers found that the combination of these meds caused serious inflammation of the liver, which could potentially cause liver failure. Patients taking either form of saquinavir plus rifampin (including any meds that contain rifampin as part of a combination) should contact their healthcare provider immediately.

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