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Lowering drug doses for dialysis. (Treatment News).

Researchers from Duke University Medical Center in North Carolina have reported that HIV-infected patients with end-stage kidney disease requiring chronic dialysis can be given much lower doses of the anti-HIV drug Epivir. A once-daily dose of 25 mg in dialysis patients provided the same amount

of drug in the body as 2 daily doses of 150 mg in patients with normal kidney function. These results could have an impact on the dosing of other anti-HIV drugs in dialysis patients. The study was published in the journal Antimicrobial Agents and Chemotherapy (46, p. 2387, 2002)

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