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Bioscience Technology

Issue Date: 09/01/2006

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1. High throughput SNP genotyping services.(Instruments & Systems: PRODUCTS) Single Nucleotide Polymorphism (SNP) genotyping is carried out using eight Illumina BeadArray instruments and custom or off-the-shelf Illumina Infinium chips or GoldenGate marker sets, for ... (PREMIUM PERIODICAL ARTICLE) 2. Triple quadrupole mass spec.(Instruments & Systems: PRODUCTS) The 6410 triple quadrupole LC/MS provides fetogram-level (10-15 grams) sensitivity. Ion optics enhance ion transmission and spectral resolution. Autotune technology and wide mass-bandwidth allow for ... (PREMIUM PERIODICAL ARTICLE) 3. Small molecule database.(Instruments & Systems: PRODUCTS) Freely available PubChem database of small molecule data, designed to support links to outside chemical information resources, is now cross-indexed with the Compound Index hosted ... (PREMIUM PERIODICAL ARTICLE) 4. Metabolite identification software.(Instruments & Systems: PRODUCTS) LightSight Software (Applied Biosystems) for metabolite identification is offered for drug discovery scientists analyzing new compounds to treat human disease on the company's mass spec ... (PREMIUM PERIODICAL ARTICLE) 5. DNA Ligation Kit.(Biochemicals & Kits: Cloning Focus) Mighty Mix DNA Ligation Kit is a one-solution pre-mix that offers efficient ligations, particularly for blunt-end ligation and TA cloning. The single solution reagent simplifies ... (PREMIUM PERIODICAL ARTICLE) 6. Clone toxic DNA.(Biochemicals & Kits: Cloning Focus) CopyCutter EPI400 E. coli cells reduce the copy number of many common plasmid vectors (including pUC, pBR, and pET) by 25-fold, allowing "toxic" genes or ... (PREMIUM PERIODICAL ARTICLE) 7. Protein-protein interaction screening.(Biochemicals & Kits: PRODUCTS) Customized yeast two-hybrid screening allows quick identification of novel binding partners for membrane or soluble proteins. Genetic screening system for integral membrane proteins offers laboratory ... (PREMIUM PERIODICAL ARTICLE) 8. Whole genome amplification, labeling.(Biochemicals & Kits: PRODUCTS) Genome-pULSe arrayCGH Whole Genome Amplification and Labeling Kit combines QIAGEN's whole genome amplification (WGA) technology, which allows amplification of very small amounts of genomic DNA ... (PREMIUM PERIODICAL ARTICLE) 9. Discover, quantitate, protein expression changes.(Biochemicals & Kits:... iTRAQ reagents offer an isobaric "tagging" strategy for discovering and quantifying protein expression changes by mass spec across multiple samples in studies ranging from biomarker ... (PREMIUM PERIODICAL ARTICLE) 10. Oncogene mutation kit.(Biochemicals & Kits: PRODUCTS) Designed to detect the T790M mutation in exon 20 of the epidermal growth factor receptor (EGFR) gene, the assay will allow drug developers to investigate ... (PREMIUM PERIODICAL ARTICLE)
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